“From osteoarthritic synovium to synovial-derived cells characterization: synovial macrophages are key effector cells”, Cristina Manferdini, Francesca Paolella, Elena Gabusi, Ylenia Silvestri, Laura Gambari, Luca Cattini, Giuseppe Filardo, Sandrine Fleury-Cappellesso, Gina Lisignoli, Arthritis Research & Therapy (2016)18:83, DOI: 10:1186/s13075-016-09834  Download the pdf here.

“Deregulation and therapeutic potential of microRNAs in arthritic diseases”, Rita VicenteDanièle NoëlYves-Marie PersFlorence Apparailly, Christian Jorgensen, Nature Reviews Rheumatology 12(2016), 211–220, DOI: 10.1038/nrrheum.2015.162 Download the pdf here.

Therapeutic application of mesenchymal stem cells in osteoarthritis”, Maxime Ruiz, Stella Cosenza, Marie Maumus, Christian Jorgensen, Danièle Noël, Expert Opinion on Biological Therapy 16(2016) 1, 33-42, DOI: 10.1517/14712598.2016.1093108 Download the pdf here.

“Adipose Mesenchymal Stem Cells Isolated after Manual or Water-jet-Assisted Liposuction Display Similar Properties”, Claire Bony, Mailys Cren, Sophie Domergue, Karine Toupet, Danièle Noël, Front. Immunol. 6(2015):655, DOI: 10.3389/fimmu.2015.00655  Download the pdf here.

“Mesenchymal stem cells for the management of inflammation in osteoarthritis: state of the art and perspectives”, Y.-M. Pers, M. Ruiz, D. Noël, C. Jorgensen, Osteoarthritis and Cartilage, 23 (2015) 11, 2027–2035, DOI: 10.1016/j.joca.2015.07.004 Download the pdf here.

“Mesenchymal stem cells derived exosomes and microparticles protect cartilage and bone from degradation in osteoarthritis”, Stella Cosenza, Maxime Ruiz, Karine Toupet, Christian Jorgensen, Danièle Noël, SCIENTIFIC RepOrTS, (2017) 7: 16214, DOI:10.1038/s41598-017-15376-8. Download the pdf here.

“Adipose stromal cells mediated switching of the pro-inflammatory profile of M1-like macrophages is facilitated by PGE2: in vitro evaluation”, C. Manferdini, F. Paolella, E. Gabusi, L. Gambari, A. Piacentini, G. Filardo, S. Fleury-Cappellesso, A. Barbero, M. Murphy, G. Lisignoli, Osteoarthritis and Cartilage 25(2017) 1161-1171, DOI: 10.1016/j.joca.2017.01.011 Download the pdf here.

“Mesenchymal stem cells-derived exosomes are more immunosuppressive than microparticles in inflammatory arthritis”, Stella Cosenza, Karine Toupet, Marie Maumus, Patricia Luz-Crawford, Olivier Blanc-Brude, Christian Jorgensen, Danièle Noël, Theranostics (2018); 8(5):1399-1410, DOI: 10.7150/thno.21072 Download the pdf here.

“Thrombospondin-1 Partly Mediates the Cartilage Protective Effect of Adipose-Derived Mesenchymal Stem Cells in Osteoarthritis”, Marie Maumus, Cristina Manferdini, Karine Toupet1, Paul Chuchana, Louis Casteilla, Mélanie Gachet, Christian Jorgensen, Gina Lisignoli, Danièle Noël, Front. Immunol. (2017) 8:1638, DOI: 10.3389/fimmu.2017.01638 Download the pdf here.

“Pathogenic or Therapeutic Extracellular Vesicles in Rheumatic Diseases: Role of Mesenchymal Stem Cell-Derived Vesicles”, Stella CosenzaMaxime RuizMarie MaumusChristian Jorgensen, Danièle Noël, Int. J. Mol. Sci. (2017), 18(4), 889, DOI: 10.3390/ijms18040889 Download the pdf here.

“Adipose Mesenchymal Stromal Cell‐Based Therapy for Severe Osteoarthritis of the Knee: A Phase I Dose‐Escalation Trial”, Yves-Marie Pers, Lars Rackwitz, Rosanna Ferreira, Oliver Pullig, Christophe Delfour, Frank Barry, Luc Sensebe, Louis Casteilla, Sandrine Fleury, Philippe Bourin, Danièle Noël, François Canovas, Catherine Cyteval, Gina Lisignoli, Joachim Schrauth, Daniel Haddad, Sophie Domergue, Ulrich Noeth, Christian Jorgensen on behalf of the ADIPOA Consortium, STEM CELLS TRANSLATIONAL MEDICINE 5(2016):847856, DOI: 10.5966/sctm.2015-0245 Download the pdf here.

“Treatment efficacy of adipose-derived stem cells in experimental osteoarthritis is driven by high synovial activation and reflected by S100A8/A9 serum levels”, R.F. Schelbergen, S. van Dalen, M. ter Huurne, J. Roth, T. Vogl, D. Noel, C. Jorgensen, W.B. van den Berg, F.A. van de Loo, A.B. Blom, P.L.E.M. van Lent, Osteoarthritis and Cartilage 22 (2014) 1158-1166, DOI: 10.1016/j.joca.2014.05.022  Download the pdf here.

“Alarmin S100A9 Induces Proinflammatory and Catabolic Effects Predominantly in the M1 Macrophages of Human Osteoarthritic Synovium”, Martijn H. van den BoschArjen B. BlomRik F. SchelbergenMarije I. KoendersFons A. van de LooWim B. van den BergThomas VoglJohannes RothPeter M. van der Kraan and Peter L. van Lent, 

“Bioreactor-based expansion of GMP grade adipose-derived mesenchymal stromal cells for clinical applications”: 50. Jahrestagung der Deutschen Gesellschaft für Transfusionsmedizin und Immunhämatologie (DGTI), Köln, 24.-27. Oktober 2017, Abstracts, Keller K., Runck M., Amann E.-M., Rojewski M., Lotfi R., Schrezenmeier H., Hesse F., Transfus Med Hemother 2017;44(suppl 1):1-94, DOI: 10.1159/000481444 Download the pdf here.

“Common leukocyte marker CD157 and FLAER allow simple, rapid and sensitive detection of PNH granulocytes and PNH monocytes”: Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie, Stuttgart, 29 September-3 Oktober 2017: Abstracts, Anliker M., Schauwecker P., Fischer C., Körper S., Höchsmann B., Schrezenmeier H., Oncol Res Treat 2017;40(suppl 3):1-308, DOI: 10.1159/000479566 Download the pdf here.

“Establishing a GMP-compliant protocol and quality controls for production of adipose derived mesenchymal stromal cells (ASC)”Joint Congress DGTI & DGI 2016, 7-10 September 2016, Nürnberg, AbstractsRojewski M., Lotfi R., Bugert P., Dengler T., Keller K., Zeplin P., Funk W., Schrezenmeier H., Transfus Med Hemother 2016;43(suppl1):1-88, DOI: 10.1159/000448382 Download the pdf here.

“IL-1β-mediated activation of adipose-derived mesenchymal stromal cells results in PMN reallocation and enhanced phagocytosis. A possible mechanism for the reduction of osteoarthritis pathology”, Stephanie C.M. van Dalen, Arjen B. Blom, Birgitte Walgreen, Annet W. Slöetjes, Monique M.A. Helsen, Edwin J.W. Geven, Thomas Vogl, Johannes Roth, Fons A.J. van de Loo, Marije I. Koenders, Louis Casteilla, Peter M. van der Kraan, Martijn H.J. van den Bosch, Peter L.E.M. van Lent., Frontiers in Immunology, 2019, Section: Inflammation, Article type: Original Research, DOI: 10.3389/fimmu.2019.01075 Download the pdf here.

“Osteoarthritic milieu affects adipose-derived mesenchymal stromal cells”, C Manferdini, F Paolella, E Gabusi, L Cattini, M Rojewski, H Schrezenmeier, O Addimanda, R Meliconi, G Lisignoli, J Orthop Res. 2019 Aug 19. DOI: 10.1002/jor.24446. Download the pdf here.

“TGFBI secreted by mesenchymal stromal cells ameliorates osteoarthritis and is detected by extracellular vesicles”, Maxime Ruiz, Karine Toupet, Marie Maumus, Pauline Rozier, Christian Jorgensen and Daniéle Noel, Biomaterials 226 (2020) 119544, 11 October 2019, DOI: 10.1016/j.biomaterials.2019.119544 Download the pdf here.