ADIPOA-2 work featured in Italian health magazine “Viversani”

The work of the ADIPOA-2 teams at the Universita Degli Studi di Padova and the Rizzoli Orthopaedic Institute has recently been featured in the popular press health magazine “Viversani” or “To Life with Health”. On pages 46-47, find the article Dal “grasso” un aiuto contro l’osteoartrosi  where Prof Riccardo Meliconi of the Reumatologia all’Instituto Ortopedico Rizzoli di Bologna and Prof Roberta Ramonda of the Rheumatology Unit University of Padova-Italy have consulted with the reporter Chiara Di Paola to feature the research.

Rizzoli Orthopaedic Institute researchers present ADIPOA-2 widely

Researchers at the Rizzoli Orthopaedic Institute in Bologna have been busy presenting ADIPOA-2 findings at a variety of national and international conferences. Below please find a list of their dissemination activities to inform and educate others in the research community of our scientific plan and findings.

  1. Oral presentation at “Le Cellule Staminali nella Medicina”. Round table forum: LE CELLULE STAMINALI NELLA MEDICINA TRASLAZIONALE “: Cellule Staminali e Osteoartrite: Il Progetto ADIPOA-2; Gina Lisignoli and Riccardo Meliconi
  2. Oral presentation at the ICRS 2018, 13-14 December 2018 Milan, Italy. Title: ADIPOA Project: Adipose-Derived Stem Cells Biological Effects; Gina Lisignoli.
  3. Oral presentation at the AICC (31st annual conference of Italian Association of Cell Culture), 27-28 November 2018 Bologna, Italy. Title: Mesenchymal stem cells and synoviocytes:development of an in vitro co-culture model; Gina Lisignoli.
  4. Oral presentation at the EORS 2018, 25- 28 September 2018, Galway, Ireland. Title: Adipose mesenchymal stromal cells characteristics are differently modulated by osteoarthritic milieu. Cristina Manferdini, Francesca Paolella, Elena Gabusi, Luca Cattini, Hubert Schrezenmeier, Gina Lisignoli.
  5. Oral presentation at the EORS 2018, 25- 28 September 2018, Galway, Ireland. Title: Switching of the pro-inflammatory profile of synovial osteoarthritic macrophages by adipose mesenchymal stromal cells; Cristina Manferdini, Francesca Paolella, Elena Gabusi, Laura Gambari,  Sandrine Fleury-Cappellesso, Andrea Barbero,  Mary Murphy, Gina Lisignoli.
  6. Oral presentation at OARSI 2018,  26 -29 April 2018, Liverpool, UK. Title: Adipose mesenchymal stromal cells determine the switching of the pro-inflammatory profile of synovial osteoarthritic macrophages; Cristina Manferdini, Francesca Paolella, Elena Gabusi, Laura Gambari,  Giuseppe Filardo, Sandrine Fleury-Cappellesso, Andrea Barbero,  Mary Murphy, Gina Lisignoli.
  7. Poster presentation at the SCR meeting 25-27 May 2017, Chieti, Italy. Title: Switching of a M1 inflammatory macrophages subset by adipose stromal cells contributes to resolution of osteoarthritic synovial tissue inflammation; C Manferdini, F Paolella, E Gabusi, L Gambari, L Cattini, A Piacentini, S Fleury-Cappellesso, A Barbero, M Murphy, G Lisignoli.
  8. Poster presentation at the EULAR 2017 14-17 June 2017 Madrid, Spain. Title: Adipose stromal cells exert specific effects on osteoarthritic synovial macrophages; Manferdini C, Paolella F., Gabusi E., Piacentini A., Gambari L., Cattini L., Fleury-Cappellesso S., Lisignoli G
  9. Oral presentation at the ICRS held 24-27 September 2016, Sorrento, IT. Title: Adipose stromal cells exert specific effects on osteoarthritic synovial macrophages; Manferdini C, Paolella F., Gabusi E., Piacentini A., Gambari L., Cattini L., Fleury-Cappellesso S.,  Lisignoli G.
  10. Poster presentation at TERMIS 27 June-04 July 2016, Uppsala, Sweden Title: Adipose stromal cells effects on osteoarthritic synovial cells are dependent by macrophages; C Manferdini, F Paolella, E Gabusi, L Gambari, L Cattini, S Fleury-Cappellesso, A Barbero, G Lisignoli.
  11. Poster presentation at the OARSI 2016 World Congress, March 31-April 3 Amsterdam, Netherlands. Title: Adipose stromal cells effects on osteoarthritic synoviocytes are dependent by macrophages; Manferdini C,  Gabusi E., Piacentini A.,  Paolella F., Fleury-Cappellesso S., Jorgensen C., Noël D., Barbero A., Lisignoli G.
  12. Poster presentation at the SCR meeting 21– 23 June 2016 Bologna, Italy. Title: Adipose stromal cells effects on osteoarthritic synovial cells are dependent by macrophages; C Manferdini1, F Paolella1, E Gabusi1, L Gambari, L Cattini, S Fleury-Cappellesso, A Barbero4, G Lisignoli

Partners at CCMI, NUI Galway offer training workshops

Our partners at the Centre for Cell Manufacturing Ireland (CCMI) based at the National University of Ireland Galway have organized a workshop series:  “Selection, Validation and Implementation of Rapid Microbiological Methods for ATMPs“. This event will take place in Galway, Ireland on the 12th and 13th of June 2019.

For more information, download the flyer here.

Coordinator Barry to speak at GISM 2019 meeting, Genoa

ADIPOA-2 Coordinator Prof Frank Barry from the Regenerative Medicine Institute, REMEDI at the National University of Ireland Galway will be a speaker and present ADIPOA-2 at a conference on the 4th and 5th of April 2019: “Research Challenges for Clinical Application of MSCs”. The two-day meeting will take place at the Centro Congressi IST Nord – Ospedale Policlinico San Martino in Genoa. Drs Milena Mastrogiacomo and Chiara Gentili, and their colleagues in the Italian Mesenchymal Stem Cell Group (GISM) at the University of Genoa are organizing this meeting.

The Italian Mesenchymal Stem Cell Group (GISM) was formed in October 2014 by 53 founding members, most of whom are researchers from the most important Italian universities and research associations. At present, GISM includes several honoured, honorary, and supportive members. The main purpose of GISM is to promote the exchange of information between researchers working in the field of mesenchymal stem cells (MSCs), giving particular emphasis to research on the clinical applications of MSCs.

Download the meeting programme here. Please click here for more information.

Frank Barry gives keynote presentation at Zoobiquity Colorado meeting

On October 5 and 6, 2018, Zoobiquity Colorado: Connecting Human and Animal Health through Regenerative Medicine will take place. Here, ADIPOA-2 Coordinator Prof Frank Barry of the Regenerative Medicine Institute at the National University of Ireland Galway will deliver a keynote presentation, ‘Cell Strategies for Arthritic Disease’.

Zoobiquity Colorado aims to uncover the astonishing connection between human and animal health by highlighting laboratory and clinical research of human and veterinary investigators and fostering future collaboration across disciplines.

Prof Frank Barry takes ADIPOA-2 on the road

ADIPOA-2 Coordinator Professor Frank Barry of NUI Galway has had a busy 2018 thus far. He has organised and been invited to present at several conferences, provide keynote talks and lead seminars around the world raising the profile of ADIPOA-2 internationally within academic and industrial circles.

Here is a list of events:

  1. Speaker on August 17 2018: Georgia Tech CMaT Annual Retreat, Madison WI, USA
  2. Invited Seminar on July 23 2018: Colorado State University Veterinary Orthopaedic Centre Fort Collins, CO, USA
  3. Keynote Speaker on July 6 2018: Whitaker Bioengineering Symposium, Galway, Ireland
  4.  Keynote Speaker; Conference and workshop organiser on June 28 2018: CALIN Cell and Gene Therapy Industry Symposium, Galway, Ireland
  5.  Invited Seminar on June 7 2018: University of Guelph School of Veterinary Medicine, Guelph, ON, Canada
  6.  Keynote Speaker on May 24 2018: Canadian Connective Tissue Conference, Toronto, ON, Canada
  7. Plenary Speaker on May 18 2018: American Society for Gene and Cell Therapy Annual Conference, Chicago, IL, USA
  8.  Keynote Speaker on May 12 2018: Canadian Bone and Joint Conference, London ON, Canada
  9. Plenary Speaker on May 2 2018: International Society for Cellular Therapy Annual Conference, Montreal, QC, Canada
  10.  Seminar Speaker in January 2018: Division of Orthopaedics, University of Toronto, ON, Canada

Here is some digital press coverage from the roadshow:

 

ADIPOA-2 features in Azienza Opedaliera di Padova June newsletter 2018

On pages 8-12 of the June 2018 Informasanità, the Azienda Ospedaliera di Padova newsletter, ADIPOA-2 is featured. The role within the project and the team at the Rheumatology Unit, Department of Medicine – DIMED, University of Padova (UNIPD) are highlighted.

Read the entire publication here:  INFORMASANITA-GIUGNO-2018

Read more about the Rheumatology Unit of the Department of Medicine (DIMED) of University of Padova here.

Cell and Gene Therapy Industry Forum in Galway addresses opportunities for innovation

Leaders in industry and science met and discussed recent advances in cell and gene therapy research and development at an industry-focused event held on Thursday, June 28, 2018, at the Meyrick Hotel in Galway, Ireland.  Industry representation included presentations from Takeda, ReNeuron, Avectas and Valitacell. ADIPOA-2 Coordinator Prof Frank Barry presented the project’s mission, progress and innovative aspects.

The emerging fields of cell and gene therapy are considered by many to be the next revolution in medicine, promising unprecedented and previously unimaginable treatments for major life-altering conditions and degenerative diseases. There are few areas of biomedical research which have attracted so much attention in recent years and been surrounded by so much expectation and promise. However, serious challenges remain in addressing manufacturing efficiency, cost reduction, clinical trials and delivery to patients.

The event sponsors were The Celtic Advanced Life Science Innovation Network, an Ireland Wales 2014-2020 programme partially funded by the European Regional Development Fund through the Welsh Government.

Speakers included: Robin Ali, University College London, Frank Barry REMEDI at NUI Galway, John Sinden, ReNeuron, Michael McGuire Avectas, Andrew Finnerty CCMI, Maria del Pilar Redondo, Takeda Europe, Mary Murphy REMEDI at NUI Galway, Stephanie Davis Valitacell and Gerry McCauliffe of Omnispirant.

Read the entire event programme: CALIN Galway Programme. 

ADIPOA-2 celebrates International Clinical Trials Day with the HRB-TMRN

EU funded projects ADIPOA-2, AUTOSTEM, NEPHSTROM and VISICORT coordinated by the Regenerative Medicine Institute (REMEDI) at National University of Ireland, Galway exhibited at a unique outreach activity targeted at primary school students. The event called the START competition was the brainchild of the Health Research Board (Ireland)’s Trials Methodology Research Network (HRB-TMRN) in Galway. In celebration of International Clinical Trials Day and to draw attention to clinical research conducted in Ireland, young people were invited to design, conduct and report on a randomized clinical trial. On May 18, 2018, three of the short-listed schools assembled at the University in Galway to visit interactive exhibitions, talk with researchers, perform mini-experiments, take part in lively science demonstrations and collect their prizes. The winning school was St. Joseph’s National School from Kinvara, County Galway.

Special thanks to Dr Siobhan Gaughan who organized the stand, Georgina Shaw who prepared the stem cell plates and to NUI Galway volunteers Dr Tina Harte, Dr Cathal Ó Flatharta, Dr. Nahidul Islam, Hannah Egan, Niamh Leonard, Dr. Emily Growney Kalaf, Claire Dooley and Dulan Hasantha Jayasooriya who volunteered their time to work with the young people on behalf of the EU funded project, STEM promotion.  The STEMinator cards used at the exhibition were designed by Cúram, NUI Galway. Also thank you to Lauren, Alibhe and Charlotte for creating the stem cell models.

Read more about the START competition here.

 

ADIPOA-2 clinical study highlighted in University of Padua publication

On March 29, 2018, the online magazine Il Bo published an update on the ADIPOA-2 clinical trial ongoing at the University of Padua and other sites. Read the story here.